wrote:
if you read my startalk you know what this is about. If you didn't,
it is this article: https://www.nrk.no/trondelag/ny-forskning-viser-at-plast-lekker-mer-miljogifter-og-farlige-kjemikalier-enn-man-har-trodd-i-vann-1.15703811
or this rapport: pubs.acs.org/doi/10.1021/acs.est.1c01103# (this is the source too)
-- this is just a summary of sorts -
Test:
* figuring if 24 "everyday" food contacting materials (FCM) leak toxic chemicals and how much
* 10 days at 40 °C in the dark which corresponds to the migration testing conditions laid out in the EU regulation for plastic FCMs

Figure 1. Heat map. In vitro toxicity of chemicals migrating from plastic consumer products. Baseline toxicity (Microtox) and oxidative stress response (AREc32) are presented as effect concentrations inducing 20% baseline toxicity (EC20) or an induction ratio of 2 (ECIR2) as well as effect levels (EL) at the highest analyzed noncytotoxic concentration. Estrogenic (YES) and antiandrogenic activities (YAAS) are shown as relative (%) activation of the human estrogen receptor α (hERα) and inhibition of the androgen receptor (hAR). Note: x, all analyzed concentrations were cytotoxic; +, food contact materials.
FCM = Food contacing materials
Microtox = Baseline toxicity
AREc32 = oxidative stress response
YES = Estrogenic
YAAS = Antiandrogenic
imgur.com/kTxrotAWhat they tested:
HDPE1 - bin liners
LDPE - lemon juice bottle
LDPE - plastic wrap
LDPE - freezer bag
LDPE - hair conditioner bottle
PS1 - yogurt cup
PS2 - fruit tray
PS3 - vegetable tray
PS4 - plastic cup
PP1 - yoghurt cup
PP2 - gummi candy packaging
PET 1 - oven bag
PVC 1 - Plastic wrap
PVC 2 - placemat
PVC 3 - pond liner
PVC 4 - floor covering
PUR 1 - scouring pad
PUR 2 - kids bath sponge
PUR 3 - acoustic foam
PUR 4 - shower slippers
PLA 1 - youghurt cup
PLA 2 - vegetable tray
PLA 3 - shampoo bottle
PLA 4 - coffe cup lid

Figure 3. Numbers of chemical features migrating from plastic products
and ratios of the abundance of each feature in the extract and the migrate (B). The left side of each graph represents features with no/low migration (migration ratio of <0.1), the right side represents features that are readily leachable, that is, they are only detected in migrates (M in B) or migrating with a ratio of >0.1. The dark gray band in (B) highlights the area in which abundance of features is similar (maximally 10-fold lower or higher) in the extracts and migrates.
* many of the migrating compounds are detected in similar levels in the extracts and the migrates, indicating they are readily leachable in water
* there were several features that we detected in much higher levels in the migrates than in the extracts, no matter the polymer type (e.g., in LDPE 4, PP 2, PUR 1, PLA 3). This implies a preferential migration into water over methanol or an additional formation during migration.
* these results have to be interpreted with caution given that the abundance of a feature in the mass spectroscopy may not be linearly related to its concentration.
* we tentatively identified 2979 unique compounds present in and/or migrating from the plastic products. This represents approximately 8% of all detected features.
* Interestingly, only 452 chemicals were covered by the ECHAdb, that is, they are registered under the European REACH regulation.
* Out of a total of 240 features, we tentatively identified 45 chemicals, including multiple carboxylic acids, alcohols, and amides (Table S10). Interestingly, the organophosphates migrating from PVC products were the only tentatively identified chemicals that are obviously related to plastic additives. In
conclusion - ish
* Our results also show that many more chemicals are migrating from plastics than previously known. The large number of compounds, and the fact that most of these remain unidentified, pinpoint the shortcomings of current scientific and regulatory approaches to the chemicals leaching from plastics.
if you read my startalk you know what this is about. If you didn't,
it is this article: https://www.nrk.no/trondelag/ny-forskning-viser-at-plast-lekker-mer-miljogifter-og-farlige-kjemikalier-enn-man-har-trodd-i-vann-1.15703811
or this rapport: pubs.acs.org/doi/10.1021/acs.est.1c01103# (this is the source too)
-- this is just a summary of sorts -
Test:
* figuring if 24 "everyday" food contacting materials (FCM) leak toxic chemicals and how much
* 10 days at 40 °C in the dark which corresponds to the migration testing conditions laid out in the EU regulation for plastic FCMs

Figure 1. Heat map. In vitro toxicity of chemicals migrating from plastic consumer products. Baseline toxicity (Microtox) and oxidative stress response (AREc32) are presented as effect concentrations inducing 20% baseline toxicity (EC20) or an induction ratio of 2 (ECIR2) as well as effect levels (EL) at the highest analyzed noncytotoxic concentration. Estrogenic (YES) and antiandrogenic activities (YAAS) are shown as relative (%) activation of the human estrogen receptor α (hERα) and inhibition of the androgen receptor (hAR). Note: x, all analyzed concentrations were cytotoxic; +, food contact materials.
FCM = Food contacing materials
Microtox = Baseline toxicity
AREc32 = oxidative stress response
YES = Estrogenic
YAAS = Antiandrogenic
imgur.com/kTxrotAWhat they tested:
HDPE1 - bin liners
LDPE - lemon juice bottle
LDPE - plastic wrap
LDPE - freezer bag
LDPE - hair conditioner bottle
PS1 - yogurt cup
PS2 - fruit tray
PS3 - vegetable tray
PS4 - plastic cup
PP1 - yoghurt cup
PP2 - gummi candy packaging
PET 1 - oven bag
PVC 1 - Plastic wrap
PVC 2 - placemat
PVC 3 - pond liner
PVC 4 - floor covering
PUR 1 - scouring pad
PUR 2 - kids bath sponge
PUR 3 - acoustic foam
PUR 4 - shower slippers
PLA 1 - youghurt cup
PLA 2 - vegetable tray
PLA 3 - shampoo bottle
PLA 4 - coffe cup lid

Figure 3. Numbers of chemical features migrating from plastic products

* many of the migrating compounds are detected in similar levels in the extracts and the migrates, indicating they are readily leachable in water
* there were several features that we detected in much higher levels in the migrates than in the extracts, no matter the polymer type (e.g., in LDPE 4, PP 2, PUR 1, PLA 3). This implies a preferential migration into water over methanol or an additional formation during migration.
* these results have to be interpreted with caution given that the abundance of a feature in the mass spectroscopy may not be linearly related to its concentration.
* we tentatively identified 2979 unique compounds present in and/or migrating from the plastic products. This represents approximately 8% of all detected features.
* Interestingly, only 452 chemicals were covered by the ECHAdb, that is, they are registered under the European REACH regulation.
* Out of a total of 240 features, we tentatively identified 45 chemicals, including multiple carboxylic acids, alcohols, and amides (Table S10). Interestingly, the organophosphates migrating from PVC products were the only tentatively identified chemicals that are obviously related to plastic additives. In
conclusion - ish
* Our results also show that many more chemicals are migrating from plastics than previously known. The large number of compounds, and the fact that most of these remain unidentified, pinpoint the shortcomings of current scientific and regulatory approaches to the chemicals leaching from plastics.